NFL Week 4 Preview and Predictions (2022)

Each week we write a preview for each game include NFL bet predictions and some narratives to consider. Whether you are looking for the best NFL bets or looking to decide which players to sit/start in your fantasy football league, this article will help keep you informed.

We’ve got an exciting week of games including a game across the pond in London!

Let’s get into the games!

Miami Dolphins vs. Cincinnati Bengals

  • Kickoff: Thursday, September 29 at 8:15 PM EST
  • Point Spread: Bengals -3.5
  • Over/Under Game Total: 47.5

The Miami Dolphins will face off against the Cincinnati Bengals at Paycor Stadium this week. The Bengals are favorites at home; the Dolphins are getting 3.5 points from Vegas.

Tua Tagovailoa will lead The Dolphins on the offense. Tagovailoa has averaged 24 pass completions and nearly 310.0 yards per game this season. This week Tagovailoa will likely struggle with the passing game against this defense. The Bengals have only allowed around 4.0 offensive yards per play this season. The Cincinnati Bengals will likely be looking to put pressure on Tua Tagovailoa in the pocket. Tagovailoa should be able to use his speed and mobility to run the ball.

The Dolphins will have a split backfield, with Raheem Mostert and Chase Edmonds sharing responsibilities of the run game.

Tyreek Hill, Jaylen Waddle, Mike Gesicki, and Chase Edmonds will be responsible for receiving for The Dolphins. This season, Jaylen Waddle has seen 10.0 targets per game; ideally, he’ll get about the same number of looks this week. Mike Gesicki has averaged 2.0 receptions per game and should see a similar amount of usage in this matchup. In addition to running the ball, Chase Edmonds will also be involved in the passing game. Edmonds has seen almost 3.0 targets per game this season and should see a similar number of looks this week.

Joe Burrow will lead The Bengals on the offense. This season Burrow has averaged 26 pass completions and over 270.0 yards per game. This week Burrow should be able to exceed his average passing performance. The Dolphins have allowed over 6.0 offensive yards per play this season. The Miami Dolphins will likely be looking to attack Joe Burrow in the pocket. Burrow should be able to use his speed and mobility to run the ball himself.

Joe Mixon will carry the majority of the run game for The Bengals.

Ja’Marr Chase, Tee Higgins, Tyler Boyd, and Hayden Hurst will be responsible for receiving for The Bengals. This season, Tee Higgins has averaged almost 6.5 targets per game. His usage should be higher this week, and he should be able to connect much more. Tyler Boyd has averaged almost 4.0 receptions per game and should see a similar amount of usage in this matchup.

Minnesota Vikings vs. New Orleans Saints

  • Kickoff: Sunday, October 2 at 9:30 AM EST
  • Point Spread: Vikings -2.5
  • Over/Under Game Total: 43.5

The Minnesota Vikings will face off against the New Orleans Saints at Tottenham Hotspur Stadium this week. This is the first of three games that will be played in London, England, this year.

The Vikings are favorites, The Saints are getting 2.5 points from Vegas.

Kirk Cousins will lead The Vikings on the offense. This season Cousins has averaged 24 pass completions and nearly 255.0 yards per game. This week Cousins should be able to exceed his average passing performance. The Saints have allowed over 4.0 offensive yards per play this season. Cousins will be able to utilize his legs and scramble out of any danger when necessary.

Dalvin Cook will carry the majority of the run game for The Vikings. This season Cook has averaged almost 2.0 yards per carry and should be able to keep up with that pace.

Justin Jefferson, Adam Thielen, Irv Smith Jr., and K.J. Osborn will be responsible for receiving for The Vikings. Justin Jefferson has averaged 6.0 receptions per game and should see a similar amount of usage in this matchup. Adam Thielen has seen nearly 6.5 targets per game; ideally, he’ll get about the same number of looks this week. Irv Smith Jr. has almost 2.5 receptions per game but should see much more usage in this matchup.

Jameis Winston will lead The Saints on the offense. Winston has averaged 24 pass completions and nearly 285.0 yards per game this season. This week Winston should be able to keep up with his usual passing pace. The Vikings have allowed 6.0 offensive yards per play this season. The Minnesota Vikings will likely be looking to attack Jameis Winston in the pocket. Winston should be able to use his speed and mobility to run the ball himself.

Alvin Kamara will carry the majority of the run game for The Saints.

The Saints will have Michael Thomas, Chris Olave, and Jarvis Landry handling the receiving. This season, Michael Thomas has seen nearly 8.0 targets per game. Ideally, he’ll get about the same number of looks this week. In addition to running the ball, Alvin Kamara will also be involved in the passing game. Kamara has seen 5.5 targets per game this season and should see a similar number of looks this week.

Buffalo Bills vs. Baltimore Ravens

  • Kickoff: Sunday, October 2 at 1:00 PM EST
  • Point Spread: Bills -3.0
  • Over/Under Game Total: 51.0

This week, the Buffalo Bills will face off against the Baltimore Ravens at M&T Bank Stadium. The Bills are favorites on the roadThe Ravens are getting 3.0 points from Vegas.

Josh Allen will lead The Bills on the offense. This season Allen has averaged over 30.0 pass completions and almost 340.0 yards per game. This week Allen should be able to keep up with his usual passing pace. The Ravens have allowed nearly 6.0 offensive yards per play this season. The Baltimore Ravens will likely be looking to attack Josh Allen in the pocket. Allen should be able to use his speed and agility to run the ball himself.

Devin Singletary will carry the majority of the run game for The Bills.

The passing game for The Bills will be handled by Stefon Diggs, Gabe Davis, Dawson Knox, and Isaiah McKenzie. Gabe Davis has averaged 5.5 targets per game; his usage should be higher this week, and he should be able to connect much more. This season, Dawson Knox has seen nearly 4.0 targets per game, ideally, he’ll get about the same number of looks this week.

Lamar Jackson will lead The Ravens on the offense. This season Jackson has averaged 18 pass completions and almost 250.0 yards per game. This week Jackson should be able to keep up with his usual passing pace. This season, The Bills have allowed nearly 160.0 passing yards per game. The Buffalo Bills will likely be looking to put pressure on Lamar Jackson in the pocket. Jackson should be able to use his speed and agility to run the ball himself.

J.K. Dobbins will carry the majority of the run game for The Ravens. This season Dobbins has averaged almost 3.5 yards per carry and should be able to well exceed that pace.

Mark Andrews, Rashod Bateman, Devin Duvernay, and Isaiah Likely will be responsible for receiving for The Ravens. This season, Rashod Bateman has averaged almost 5.5 targets per game. His usage should be higher this week, and he should be able to connect much more. This season, Devin Duvernay has seen nearly 3.0 targets per game, ideally, he’ll get about the same number of looks this week. This season, Isaiah Likely has averaged nearly 4.0 targets per game. His usage should be higher this week, and he should be able to connect much more.

Washington Commanders vs. Dallas Cowboys

  • Kickoff: Sunday, October 2 at 1:00 PM EST
  • Point Spread: Cowboys -3.0
  • Over/Under Game Total: 41.5

The Washington Commanders will face off against the Dallas Cowboys at AT&T Stadium this week. The Cowboys are favorites at homeThe Commanders are getting 3.0 points from Vegas.

Carson Wentz will lead The Commanders on the offense. This season Wentz has averaged nearly 26.0 pass completions and nearly 285.0 yards per game. This week Wentz will likely struggle with the passing game against this defense. The Cowboys have only allowed around 4.0 offensive yards per play this season. The Dallas Cowboys will likely be looking to attack Carson Wentz in the pocket. Wentz should be able to use his speed and agility to run the ball himself.

Antonio Gibson will carry the majority of the run game for The Commanders.

The passing game for The Commanders will be handled by Terry McLaurin, Curtis Samuel, Jahan Dotson, and Logan Thomas. Terry McLaurin has averaged 4.0 receptions per game and should see a similar amount of usage in this matchup. Jahan Dotson has averaged over 2.0 receptions per game and should see a similar amount of usage in this matchup. This season, Logan Thomas has seen nearly 4.0 targets per game, ideally, he’ll get about the same number of looks this week.

Cooper Rush will lead The Cowboys on the offense. Rush has averaged over 14.0 pass completions and over 170.0 yards per game this season. This week Rush should be able to exceed his average passing performance. This season, The Commanders have allowed over 270.0 passing yards per game. The Washington Commanders will likely be looking to attack Cooper Rush in the pocket. Rush will be able to utilize his legs and scramble out of any danger when necessary.

Ezekiel Elliott will carry the majority of the run game for The Cowboys. Elliott has averaged almost 1.5 yards per carry this season and should be able to keep up with that pace.

The Cowboys will have CeeDee Lamb, Dalton Schultz, (possibly) Michael Gallup, and Noah Brown handling the receiving. CeeDee Lamb has averaged nearly 6.0 receptions per game and should see a similar amount of usage in this matchup. Dalton Schultz has averaged nearly 4.0 receptions per game and should see a similar amount of usage in this matchup. 

Michael Gallup could possibly make his return to the field this week. If he does, this could help spread the defensive matchups because they won’t be able to simply stack up on CeeDee Lamb and Noah Brown. He said that he physically feels ready. 

Cleveland Browns vs. Atlanta Falcons

  • Kickoff: Sunday, October 2 at 1:00 PM EST
  • Point Spread: Browns -1.5
  • Over/Under Game Total: 48.0

This week, the Cleveland Browns will face off against the Atlanta Falcons at Mercedes-Benz Stadium. The Browns are favorites on the roadThe Falcons are getting 1.5 points from Vegas.

Jacoby Brissett will lead The Browns on the offense. This season Brissett has averaged 20 pass completions and nearly 200.0 yards per game. This week Brissett should be able to exceed his average passing performance. This season, The Falcons have given up nearly 6 passing touchdowns. The Atlanta Falcons will likely be looking to attack Jacoby Brissett in the pocket. Brissett should be able to use his speed and agility to run the ball himself.

Nick Chubb will carry the majority of the run game for The Browns.

The Browns will have Amari Cooper, Donovan Peoples-Jones, David Njoku, and Harrison Bryant handling the receiving. This season, Donovan Peoples-Jones has averaged over 4.0 targets per game. His usage should be higher this week, and he should be able to connect much more. Harrison Bryant has averaged almost 2.0 receptions per game and should see a similar amount of usage in this matchup.

Marcus Mariota will lead The Falcons on the offense. Mariota has averaged 16 pass completions and nearly 215.0 yards per game this season. This week Mariota should be able to exceed his average passing performance. This season, The Browns have given up nearly 6 passing touchdowns. The Cleveland Browns will likely be looking to attack Marcus Mariota in the pocket. Mariota should be able to use his speed and mobility to run the ball himself.

Cordarrelle Patterson will carry the majority of the run game for The Falcons.

The passing game for The Falcons will be handled by Drake London, Kyle Pitts, and Olamide Zaccheaus. Drake London has averaged nearly 6.0 receptions per game and should see a similar amount of usage in this matchup. This season, Kyle Pitts has averaged 6.0 targets per game; his usage should be higher this week, and he should be able to connect much more. In addition to running the ball, Cordarrelle Patterson will also be involved in the passing game. This season Patterson has seen almost 2.5 targets per game and should see a similar number of looks this week.

Seattle Seahawks vs. Detroit Lions

  • Kickoff: Sunday, October 2 at 1:00 PM EST
  • Point Spread: Lions -4.0
  • Over/Under Game Total: 48.0

This week, the Seattle Seahawks will face off against the Detroit Lions at Ford Field. The Lions are favorites at homeThe Seahawks are getting 4.0 points from Vegas.

Geno Smith will lead The Seahawks on the offense. This season Smith has averaged 26 pass completions and almost 240.0 yards per game. This week Smith should be able to exceed his average passing performance. This season, The Lions have given up almost 6 passing touchdowns. The Detroit Lions will likely be looking to attack Geno Smith in the pocket. Smith should be able to use his speed and agility to run the ball himself.

Rashaad Penny will carry the majority of the run game for The Seahawks.

Tyler Lockett, DK Metcalf, Noah Fant, and Will Dissly will be responsible for receiving for The Seahawks. DK Metcalf has averaged almost 6.0 receptions per game and should see a similar amount of usage in this matchup. Noah Fant has averaged nearly 2.0 receptions per game and should see a similar amount of usage in this matchup.

Jared Goff will lead The Lions on the offense. This season Goff has averaged 22 pass completions and nearly 250.0 yards per game. This week Goff should be able to exceed his average passing performance. This season, The Seahawks have given up 3.0 passing touchdowns. The Seattle Seahawks will likely be looking to put pressure on Jared Goff in the pocket. Goff will be able to utilize his legs and scramble out of any danger when necessary.

Jamaal Williams will carry the majority of the run game for The Lions.

Amon-Ra St. Brown, DJ Chark Jr., T.J. Hockenson, and Josh Reynolds will be responsible for receiving for The Lions. This season, Amon-Ra St. Brown has seen over 10.0 targets per game, ideally, he’ll get about the same number of looks this week. This season, DJ Chark Jr. has averaged 6.0 targets per game. His usage should be higher this week, and he should be able to connect much more. T.J. Hockenson has nearly 4.0 receptions per game but should see much more usage in this matchup.

Los Angeles Chargers vs. Houston Texans

  • Kickoff: Sunday, October 2 at 1:00 PM EST
  • Point Spread: Chargers -5.0
  • Over/Under Game Total: 44.0

The Los Angeles Chargers will face off against the Houston Texans at NRG Stadium this week. The Chargers are favorites on the roadThe Texans are getting 5.0 points from Vegas.

Justin Herbert will lead The Chargers on the offense. Herbert has averaged 28 pass completions and nearly 305.0 yards per game this season. This week Herbert should be able to keep up with his usual passing pace. The Texans have allowed nearly 6.0 offensive yards per play this season. The Houston Texans will likely be looking to put pressure on Justin Herbert in the pocket. Herbert will be able to utilize his legs and scramble out of any danger when necessary.

Austin Ekeler will carry the majority of the run game for The Chargers.

Mike Williams, Joshua Palmer, and Gerald Everett will handle the receiving game for The Chargers. Mike Williams has nearly 4.0 receptions per game but should see much more usage in this matchup. Joshua Palmer has averaged over 4.0 receptions per game and should see a similar amount of usage in this matchup. In addition to running the ball, Austin Ekeler will also be involved in the passing game. Ekeler has almost 7.5 targets per game this season and should expect a similar number of looks this week. Gerald Everett has seen nearly 6.0 targets per game, ideally, he’ll get about the same number of looks this week.

Davis Mills will lead The Texans on the offense. The Los Angeles Chargers will likely be looking to attack Davis Mills in the pocket. This season Mills has averaged 20 pass completions and nearly 220.0 yards per game. This week Mills should be able to exceed his average passing performance. This season, The Chargers have given up nearly 6 passing touchdowns.

Dameon Pierce will carry the majority of the run game for The Texans.

The Texans will have Brandin Cooks, Nico Collins, Chris Moore, and Rex Burkhead handling the receiving. Brandin Cooks has over 4.0 receptions per game but should see much more usage in this matchup. This season, Nico Collins has averaged nearly 5.5 targets per game; his usage should be higher this week, and he should be able to connect much more. This season, Chris Moore has averaged nearly 4.0 targets per game. His usage should be higher this week, and he should be able to connect much more. In addition to running the ball, Rex Burkhead will also be involved in the passing game. This season, Burkhead has nearly 5.5 targets per game and should expect a similar number of looks this week.

Tennessee Titans vs. Indianapolis Colts

  • Kickoff: Sunday, October 2 at 1:00 PM EST
  • Point Spread: Colts -3.0
  • Over/Under Game Total: 42.5

The Tennessee Titans will face off against the Indianapolis Colts at Lucas Oil Stadium this week. The Colts are favorites at homeThe Titans are getting 3.0 points from Vegas.

Ryan Tannehill will lead The Titans on the offense. Tannehill has averaged 16 pass completions and nearly 215.0 yards per game this season. This week Tannehill should be able to exceed his average passing performance. This season, The Colts have allowed almost 240.0 passing yards per game. Tannehill should be able to use his speed and mobility to run the ball himself.

Derrick Henry will carry the majority of the run game for The Titans.

The passing game for The Titans will be handled by Robert Woods, Treylon Burks, Nick Westbrook-Ikhine, and Austin Hooper. This season, Robert Woods has averaged nearly 5.5 targets per game; his usage should be higher this week, and he should be able to connect much more. This season, Treylon Burks has averaged over 4.0 targets per game; his usage should be higher this week, and he should be able to connect much more. This season, Nick Westbrook-Ikhine has averaged 3.0 targets per game. His usage should be higher this week, and he should be able to connect much more. This season, Austin Hooper has averaged nearly 2.0 targets per game; his usage should be higher this week, and he should be able to connect much more.

Matt Ryan will lead The Colts on the offense. This season Ryan has averaged over 24.0 pass completions and over 255.0 yards per game. This week Ryan should be able to keep up with his usual passing pace. This season, The Titans have allowed almost 260.0 passing yards per game. The Tennessee Titans will likely be looking to attack Matt Ryan in the pocket. Ryan will be able to utilize his legs and scramble out of any danger when necessary.

Jonathan Taylor will carry the majority of the run game for The Colts. This season Taylor has averaged nearly 2.0 yards per carry and should be able to keep up with that pace.

Michael Pittman Jr., Parris Campbell, Nyheim Hines, and Alec Pierce will be responsible for receiving for The Colts. Parris Campbell has averaged over 2.0 targets per game; his usage should be higher this week, and he should be able to connect much more. In addition to running the ball, Nyheim Hines will also be involved in the passing game. Hines has almost 6.0 targets per game this season and should expect a similar number of looks this week. Alec Pierce has almost 2.0 receptions per game but should see much more usage in this matchup.

Chicago Bears vs. New York Giants

  • Kickoff: Sunday, October 2 at 1:00 PM EST
  • Point Spread: Giants -3.5
  • Over/Under Game Total: 39.5

This week, the Chicago Bears will face off against the New York Giants at MetLife Stadium. The Giants are favorites at homeThe Bears are getting 3.5 points from Vegas.

Justin Fields will lead The Bears on the offense. This season Fields has averaged nearly 6.0 pass completions and nearly 100.0 yards per game. This week Fields should be able to exceed his average passing performance. This season, The Giants have given up nearly 3 passing touchdowns. Fields should be able to use his speed and agility to run the ball himself.

Khalil Herbert will carry the majority of the run game for The Bears.

Darnell Mooney, Equanimeous St. Brown, and Cole Kmet will handle the passing game for The Bears. Darnell Mooney has almost 1.5 receptions per game but should see much more usage in this matchup. Equanimeous St. Brown has nearly 1.5 receptions per game but should see much more usage in this matchup. This season, Cole Kmet has averaged almost 2.0 targets per game. His usage should be higher this week, and he should be able to connect much more.

Daniel Jones will lead The Giants on the offense. This season Jones has averaged nearly 18.0 pass completions and nearly 185.0 yards per game. This week Jones should be able to exceed his average passing performance. This season, The Bears have given up 3.0 passing touchdowns. The Chicago Bears will likely be looking to attack Daniel Jones in the pocket. Jones should be able to use his speed and mobility to run the ball himself.

Saquon Barkley will carry the majority of the run game for The Giants.

The passing game for The Giants will be handled by Richie James Jr., Saquon Barkley, David Sills V, and Kenny Golladay. Richie James Jr. has averaged nearly 4.0 receptions per game and should see a similar amount of usage in this matchup. In addition to running the ball, Saquon Barkley will also be involved in the passing game. This season, Barkley has 5.0 targets per game and should expect a similar number of looks this week. David Sills V has nearly 2.0 receptions per game but should see much more usage in this matchup. Kenny Golladay has nearly 0.0 receptions per game but should see much more usage in this matchup.

New York Jets vs. Pittsburgh Steelers

  • Kickoff: Sunday, October 2 at 1:00 PM EST
  • Point Spread: Steelers -3.0
  • Over/Under Game Total: 41.5

The New York Jets will face off against the Pittsburgh Steelers at Acrisure Stadium this week. The Steelers are favorites at homeThe Jets are getting 3.0 points from Vegas.

Zach Wilson will lead The Jets on the offense. This season Wilson has averaged 0 pass completions and 0.0 yards per game. This week Wilson should be able to exceed his average passing performance. The Steelers have allowed almost 6.0 offensive yards per play this season. The Pittsburgh Steelers will likely be looking to attack Zach Wilson in the pocket. Wilson should be able to use his speed and mobility to run the ball himself.

The Jets will have a split backfield with Michael Carter and Breece Hall sharing responsibilities of the run game.

The passing game for The Jets will be handled by Garrett Wilson, Elijah Moore, Corey Davis, and Tyler Conklin. Elijah Moore has averaged 4.0 receptions per game and should see a similar amount of usage in this matchup.

Mitch Trubisky will lead The Steelers on the offense. Trubisky has averaged 20 pass completions and almost 190.0 yards per game this season. This week Trubisky should be able to exceed his average passing performance. This season, The Jets have given up over 6 passing touchdowns. Trubisky should be able to use his speed and mobility to run the ball.

Najee Harris will carry the majority of the run game for The Steelers.

The Steelers will have Diontae Johnson, Chase Claypool, Pat Freiermuth, and George Pickens handling the receiving. Diontae Johnson has averaged nearly 6.0 receptions per game and should see a similar amount of usage in this matchup. This season, Chase Claypool has seen 6.0 targets per game, ideally, he’ll get about the same number of looks this week. This season, Pat Freiermuth has averaged 7.0 targets per game. His usage should be higher this week, and he should be able to connect much more. George Pickens has nearly 2.0 receptions per game but should see much more usage in this matchup.

Jacksonville Jaguars vs. Philadelphia Eagles

  • Kickoff: Sunday, October 2 at 1:00 PM EST
  • Point Spread: Eagles -6.5
  • Over/Under Game Total: 47.0

The Jacksonville Jaguars will face off against the Philadelphia Eagles at Lincoln Financial Field this week. The Eagles are favorites at homeThe Jaguars are getting 6.5 points from Vegas.

Trevor Lawrence will lead The Jaguars on the offense. Lawrence has averaged over 24.0 pass completions this season and almost 260.0 yards per game. This week Lawrence should be able to keep up with his usual passing pace. The Eagles have only allowed around 190.0 passing yards per game this season. Still, Trevor Lawrence and the Jaguars are really starting to sync; it wouldn’t surprise me for Trevor Lawrence to continue on his run of solid passing. The Philadelphia Eagles will likely be looking to attack Trevor Lawrence in the pocket. Lawrence should be able to use his speed and agility to run the ball himself.

James Robinson will carry the majority of the run game for The Jaguars.

Christian Kirk, Marvin Jones Jr., Zay Jones, and Evan Engram will be responsible for receiving for The Jaguars. This season, Christian Kirk has seen 9.0 targets per game, ideally, he’ll get about the same number of looks this week. Marvin Jones Jr. has almost 4.0 receptions per game but should see much more usage in this matchup.

Jalen Hurts will lead The Eagles on the offense. This season Hurts averaged 22 pass completions and over 305.0 yards per game. This week Hurts will likely struggle with the passing game against this defense. The Jaguars have allowed almost 6.0 offensive yards per play this season. The Jacksonville Jaguars will likely be looking to attack Jalen Hurts in the pocket. Hurts should be able to use his speed and mobility to run the ball himself.

Miles Sanders will carry the majority of the run game for The Eagles.

A.J. Brown, DeVonta Smith, and Dallas Goedert will be responsible for receiving for The Eagles. Dallas Goedert has averaged nearly 4.0 receptions per game and should see a similar amount of usage in this matchup.

Arizona Cardinals vs. Carolina Panthers

  • Kickoff: Sunday, October 2 at 4:05 PM EST
  • Point Spread: Panthers -1.5
  • Over/Under Game Total: 42.5

The Arizona Cardinals will face off against the Carolina Panthers at Bank of America Stadium this week. The Panthers are favorites at homeThe Cardinals are getting 1.5 points from Vegas.

Kyler Murray will lead The Cardinals on the offense. Murray has averaged 30 pass completions and nearly 260.0 yards per game this season. This week Murray should be able to keep up with his usual passing pace. This season, The Panthers have allowed nearly 210.0 passing yards per game. Murray should be able to use his speed and agility to run the ball himself.

James Conner will carry the majority of the run game for The Cardinals.

The Cardinals will have Marquise Brown and Zach Ertz handling the receiving. Additionally, Rondale Moore could make his return after missing the first three games this season. He was back at practice this week for the first time.

Baker Mayfield will lead The Panthers on the offense. This season Mayfield has averaged 14 pass completions and almost 185.0 yards per game. This week Mayfield should be able to exceed his average passing performance. The Cardinals have allowed over 6.0 offensive yards per play this season. Mayfield should be able to use his speed and mobility to run the ball himself.

Christian McCaffrey will carry the majority of the run game for The Panthers. This season McCaffrey has averaged nearly 2.0 yards per carry and should be able to keep up with that pace.

DJ Moore, Christian McCaffrey, Robbie Anderson, and Shi Smith will be responsible for receiving for The Panthers. This season, DJ Moore has averaged 6.0 targets per game; his usage should be higher this week, and he should be able to connect much more. In addition to running the ball, Christian McCaffrey will also be involved in the passing game. McCaffrey has seen nearly 5.0 targets per game this season and should see a similar number of looks this week. Robbie Anderson has over 2.0 receptions per game but should see much more usage in this matchup. Shi Smith has averaged nearly 4.0 targets per game; his usage should be higher this week, and he should be able to connect much more.

New England Patriots vs. Green Bay Packers

  • Kickoff: Sunday, October 2 at 4:25 PM EST
  • Point Spread: Packers -9.5
  • Over/Under Game Total: 40.5

The New England Patriots will face off against the Green Bay Packers at Lambeau Field this week. The Packers are favorites at homeThe Patriots are getting 9.5 points from Vegas.

Brian Hoyer will lead The Patriots on the offense. This season Hoyer has averaged 0 pass completions and 0.0 yards per game. This week Hoyer should be able to exceed his average passing performance. This season, The Packers have given up 3.0 passing touchdowns. The Green Bay Packers will likely be looking to put pressure on Brian Hoyer in the pocket.

The Patriots will have a split backfield with Damien Harris and Rhamondre Stevenson sharing responsibilities of the run game.

The passing game for The Patriots will be handled by Jakobi Meyers, DeVante Parker, Nelson Agholor, and Hunter Henry. DeVante Parker has averaged nearly 4.0 targets per game; his usage should be higher this week, and he should be able to connect much more. This season, Hunter Henry has averaged almost 2.0 targets per game; his usage should be higher this week, and he should be able to connect much more.

Aaron Rodgers will lead The Packers on the offense. This season Rodgers has averaged 22 pass completions and nearly 230.0 yards per game. This week Rodgers should be able to exceed his average passing performance. The Patriots have allowed nearly 6.0 offensive yards per play this season. The New England Patriots will likely be looking to attack Aaron Rodgers in the pocket. Rodgers should be able to use his speed and agility to run the ball himself.

The Packers will have a split backfield with AJ Dillon and Aaron Jones sharing responsibilities of the run game.

The receiving game for The Packers will be handled by Allen Lazard, Romeo Doubs, Robert Tonyan, and Aaron Jones. Allen Lazard has 3.0 receptions per game but should see much more usage in this matchup. Robert Tonyan has averaged almost 4.0 receptions per game and should see a similar amount of usage in this matchup. In addition to running the ball, Aaron Jones will also be involved in the passing game. Jones has 4.0 targets per game this season and should expect a similar number of looks this week.

Denver Broncos vs. Las Vegas Raiders

  • Kickoff: Sunday, October 2 at 4:25 PM EST
  • Point Spread: Raiders -2.5
  • Over/Under Game Total: 45.5

This week, the Denver Broncos will face off against the Las Vegas Raiders at Allegiant Stadium. The Raiders are favorites at homeThe Broncos are getting 2.5 points from Vegas.

Russell Wilson (Let’s ride!) will lead The Broncos on the offense. This season Wilson has averaged nearly 20.0 pass completions and almost 250.0 yards per game. This week Wilson should be able to exceed his average passing performance. This season, The Raiders have given up nearly 6 passing touchdowns. Wilson should be able to use his speed and agility to run the ball himself.

The Broncos will have a split backfield with Javonte Williams and Melvin Gordon III sharing responsibilities of the run game.

The Broncos will have Courtland Sutton, Jerry Jeudy, Albert Okwuegbunam, and Javonte Williams handling the receiving. Jerry Jeudy has almost 2.5 receptions per game but should see much more usage in this matchup. Albert Okwuegbunam has 2.0 receptions per game but should see much more usage in this matchup. In addition to running the ball, Javonte Williams will also be involved in the passing game. This season Williams has seen 7.0 targets per game and should see a similar number of looks this week.

Derek Carr will lead The Raiders on the offense. Carr has averaged 24 pass completions and almost 285.0 yards per game this season. This week Carr should be able to exceed his average passing performance. This season, The Broncos have allowed 170 passing yards per game. The Denver Broncos will likely be looking to put pressure on Derek Carr in the pocket. Carr will be able to utilize his legs and scramble out of any danger when necessary.

Josh Jacobs will carry the majority of the run game for The Raiders. This season Jacobs has averaged nearly 2.0 yards per carry and should be able to keep up with that pace.

Davante Adams, Hunter Renfrow, Darren Waller, and Mack Hollins will be responsible for receiving for The Raiders. Davante Adams has almost 6.0 receptions per game but should see much more usage in this matchup. Hunter Renfrow has averaged over 4.0 receptions per game and should see a similar amount of usage in this matchup. This season, Darren Waller has seen almost 6.5 targets per game, ideally, he’ll get about the same number of looks this week.

Kansas City Chiefs vs. Tampa Bay Buccaneers

  • Kickoff: Sunday, October 2 at 8:20 PM EST
  • Point Spread: Chiefs -1.5
  • Over/Under Game Total: 45.0

The Kansas City Chiefs will face off against the Tampa Bay Buccaneers at Raymond James Stadium this week. Due to Hurricane Ian, there is a contingency plan in place to move this game to Minneapolis if need be, but for now, it is still playing in Tampa Bay.

The Chiefs are favorites on the roadThe Buccaneers are getting 1.5 points from Vegas.

Patrick Mahomes will lead The Chiefs on the offense. Mahomes has averaged 24 pass completions and nearly 285.0 yards per game this season. This week Mahomes should be able to keep up with his usual passing pace. This season, The Buccaneers have given up 3.0 passing touchdowns. The Tampa Bay Buccaneers will likely be looking to attack Patrick Mahomes in the pocket. Mahomes should be able to use his speed and agility to run the ball himself.

Clyde Edwards-Helaire will carry the majority of the run game for The Chiefs.

The passing game for The Chiefs will be handled by Travis Kelce, Marquez Valdes-Scantling, JuJu Smith-Schuster, and Mecole Hardman. This season, Travis Kelce has seen 8.0 targets per game, ideally, he’ll get about the same number of looks this week. This season, Marquez Valdes-Scantling has seen 6.0 targets per game, ideally, he’ll get about the same number of looks this week. This season, JuJu Smith-Schuster has seen over 6.0 targets per game, ideally, he’ll get about the same number of looks this week. This season, Mecole Hardman has averaged almost 4.0 targets per game; his usage should be higher this week, and he should be able to connect much more.

Tom Brady will lead The Buccaneers on the offense. This season Brady has averaged 22 pass completions and almost 225.0 yards per game. This week Brady should be able to exceed his average passing performance. This season, The Chiefs have given up over 6 passing touchdowns. The Kansas City Chiefs will likely be looking to attack Tom Brady in the pocket.

Leonard Fournette will carry the majority of the run game for The Buccaneers. This season Fournette has averaged almost 1.5 yards per carry and should be able to keep up with that pace.

Mike Evans, Russell Gage, Julio Jones, and Leonard Fournette will be responsible for receiving for The Buccaneers. Mike Evans has 4.0 receptions per game but should see much more usage in this matchup. Julio Jones has averaged nearly 4.0 targets per game; his usage should be higher this week, and he should be able to connect much more. In addition to running the ball, Leonard Fournette will also be involved in the passing game. Fournette has 4.0 targets per game this season and should expect a similar number of looks this week.

Los Angeles Rams vs. San Francisco 49ers

  • Kickoff: Monday, October 3 at 8:15 PM EST
  • Point Spread: 49ers -1.5
  • Over/Under Game Total: 42.5

The Los Angeles Rams will face off against the San Francisco 49ers at Levi’s Stadium this week. The 49ers are favorites at homeThe Rams are getting 1.5 points from Vegas.

Matthew Stafford will lead The Rams on the offense. Stafford has averaged 24 pass completions and nearly 255.0 yards per game this season. This week Stafford should be able to exceed his average passing performance. The 49ers have allowed almost 4.0 offensive yards per play this season. The San Francisco 49ers will likely be looking to attack Matthew Stafford in the pocket. Stafford will be able to utilize his legs and scramble out of any danger when necessary.

The Rams will have a split backfield with Cam Akers and Darrell Henderson Jr. sharing responsibilities of the run game.

The Rams will have Cooper Kupp, Tyler Higbee, Allen Robinson II, and Ben Skowronek handling the receiving. Allen Robinson II has averaged 4.0 targets per game; his usage should be higher this week.

Jimmy Garoppolo will lead The 49ers on the offense. This season Garoppolo has averaged nearly 14.0 pass completions and almost 185.0 yards per game. This week Garoppolo should be able to exceed his average passing performance. This season, The Rams have given up almost 6 passing touchdowns. The Los Angeles Rams will likely be looking to put pressure on Jimmy Garoppolo in the pocket. Garoppolo will be able to utilize his legs and scramble out of any danger when necessary.

Jeff Wilson Jr. will carry most of the run game for The 49ers.

The 49ers will have Deebo Samuel, George Kittle, Brandon Aiyuk, and Jauan Jennings handling the receiving. This season, Deebo Samuel has averaged nearly 6.0 targets per game; his usage should be higher this week, and he should be able to connect much more. This season, George Kittle has seen 5.0 targets per game, ideally, he’ll get about the same number of looks this week. Brandon Aiyuk has averaged almost 4.0 receptions per game and should see a similar amount of usage in this matchup. Jauan Jennings has averaged 2.0 receptions per game and should see a similar amount of usage in this matchup.